Related Experiment Video
Updated: Aug 13, 2026

Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
Published on: January 22, 2018
Macular translocation for subfoveal choroidal neovascularization in angioid streaks
D B Roth1, M Estafanous, H Lewis
1Cole Eye Institute, The Cleveland Clinic Foundation, 9500 Euclid Av/i30, Cleveland, Ohio 44195, USA.
Purpose:
To report a case of visual improvement after macular translocation performed for a subfoveal choroidal neovascular membrane in a patient with pseudoxanthoma elasticum and angioid streaks.
Methods:
The fovea was translocated inferiorly by scleral imbrication, intentional retinal detachment with a small posterior retinotomy, and partial fluid-air exchange. The choroidal neovascular membrane was photocoagulated 1 week later.
Results:
The visual acuity of the patient improved from 20/125 to 20/40. The center of the foveal avascular zone was moved inferiorly 844 microm. The choroidal neovascular membrane was extrafoveal after translocation and was treated with laser photocoagulation.
Conclusion:
Macular translocation may be considered in the management of subfoveal choroidal neovascular membrane in patients with pseudoxanthoma elasticum and angioid streaks.

