Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Statins: intervention studies, facts and perspectives].

V Durlach1

  • 1Service d'Endocrinologie-Maladies Métaboliques et Médecine Interne - Hôpital Robert Debré, rue du Général Koenig, 51092 Reims Cedex. vdurlach@chu-reims.fr

Annales D'Endocrinologie
|March 10, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consensus statement on the management of dyslipidaemias in adults.

Annales d'endocrinologie·2017
Same author

Consensus statement on the management of dyslipidaemias in adults.

Diabetes & metabolism·2016
Same author

Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients.

Diabetes & metabolism·2014
Same author

Association of endothelial lipase Thr111Ile polymorphism with lipid metabolism and microvascular complications in type 2 diabetic patients.

Diabetes & metabolism·2010
Same author

[Evaluation of prescription and interpretation of microalbuminuria by general practitioners].

Annales de biologie clinique·2009
Same author

[Chronic use of proton-pump inhibitors associated with giardiasis: A rare cause of hypomagnesemic hypoparathyroidism?].

Annales d'endocrinologie·2008
Same journal

[18F]F-DOPA and [18F]F-FDG PET/CT for staging advanced medullary thyroid cancer.

Annales d'endocrinologie·2026
Same journal

Corrigendum to 'Pink adipose tissue: A paradigm of adipose tissue plasticity' [Ann. Endocrinol. 85 (2004) 248-51].

Annales d'endocrinologie·2026
Same journal

Intraoperative location of parathyroid glands during total thyroidectomy: a systematic review of the literature according to the PRISMA method.

Annales d'endocrinologie·2026
Same journal

Clinical and genetic diagnosis of PHP1A associated with hypogonadism in a young male: A case report.

Annales d'endocrinologie·2026
Same journal

Autoimmune features in acquired generalized lipodystrophy and anti-perilipin 1 antibodies: A case report.

Annales d'endocrinologie·2026
Same journal

The diagnostic challenge of occult glucocorticoid exposure causing Cushing's syndrome.

Annales d'endocrinologie·2026
See all related articles

Statins effectively lower LDL cholesterol, reducing cardiovascular events in primary and secondary prevention. Ongoing research will clarify optimal LDL targets, potential risks, and broader applications of these hypocholesterolemic drugs.

Area of Science:

  • Pharmacology
  • Cardiovascular Medicine

Context:

  • HMG-CoA reductase inhibitors (statins) are primary lipid-lowering drugs.
  • Clinical trials demonstrate statins reduce coronary events and mortality.

Purpose:

  • To review the established benefits of statins in cardiovascular disease prevention.
  • To identify unresolved questions regarding statin therapy and future research directions.

Summary:

  • Statins significantly decrease LDL cholesterol, raise HDL cholesterol, and lower triglycerides.
  • Large trials confirm statins reduce coronary morbidity and mortality in secondary and primary prevention.
  • Unanswered questions include optimal LDL targets, risks, applicability to diverse populations, and benefits in acute coronary syndromes.

Impact:

Related Experiment Videos

  • Statins are crucial for managing hypercholesterolemia and preventing cardiovascular events.
  • Future research will refine statin treatment protocols and explore their expanded therapeutic roles, including potential pleiotropic effects.