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[Neovascular glaucoma following proton-beam therapy. Case report].
F D'Hermies1, A Meyer, X Morel
1Service d'Ophtalmologie, Hôtel-Dieu, 1, place du Parvis Notre-Dame, F-75181 Paris Cedex 04.
Journal Francais D'Ophtalmologie
|March 10, 2001
Summary
A patient with posterior choroid melanoma underwent proton-beam irradiation. Seven years later, complications including neovascular glaucoma led to enucleation, highlighting treatment consequences.
Area of Science:
- Ophthalmology
- Oncology
- Radiation Oncology
Background:
- Posterior choroid melanoma is a rare intraocular malignancy.
- Proton-beam irradiation is a common treatment for choroid melanoma.
- Long-term follow-up is crucial for monitoring treatment efficacy and complications.
Observation:
- A 52-year-old male patient presented with a posterior choroid melanoma (6mm thickness, 11.9mm diameter, mushroom shape).
- Initial investigations revealed no metastatic disease; the patient received proton-beam irradiation.
- Seven years post-treatment, the patient developed increased intraocular pressure, cataract, and pain, leading to enucleation.
Findings:
- Histologic analysis confirmed tumor-related changes and treatment sequelae in both anterior and posterior eye segments.
- Neovascular glaucoma was identified as a significant complication.
- The patient's vision was completely lost, and the eye became painful prior to enucleation.
Implications:
- Neovascular glaucoma is a frequent and severe complication following choroid melanoma treatment.
- Enucleation remains a necessary intervention for eyes with intractable neovascular glaucoma and vision loss.
- Understanding long-term treatment effects is vital for managing intraocular tumors and preventing severe complications.