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[Acute lymphoblastic leukemia and vitreous infiltration. A case study].
Journal Francais D'Ophtalmologie
|March 10, 2001
Summary
Vitreous infiltration from acute lymphoblastic leukemia is rare. Vitrectomy surgery successfully restored vision in a child with leukemia, offering a stable outcome after chemotherapy failed.
Area of Science:
- Ophthalmology
- Hematology
- Pediatric Oncology
Background:
- Acute lymphoblastic leukemia (ALL) infiltration of the vitreous humor is an uncommon presentation.
- Ocular involvement in ALL can lead to significant visual impairment, particularly in pediatric cases.
Observation:
- A 5-year-old child with acute type-2 lymphoblastic leukemia presented with bilateral dense vitreous cellular infiltration.
- This infiltration caused severe vision loss, with the child able to count fingers only at 20 cm.
Findings:
- Standard chemotherapy did not resolve the vitreous infiltration.
- Bilateral vitrectomy was performed, leading to a marked improvement in visual acuity to 6/10 in both eyes.
- Visual outcomes remained stable at a 3-year follow-up post-surgery.
Implications:
- Vitrectomy is a viable surgical option for managing persistent vitreous infiltration in pediatric ALL when chemotherapy is ineffective.
- Early surgical intervention can potentially restore vision and improve quality of life in affected children.
- This case highlights the importance of considering ocular complications in pediatric leukemia and the role of ophthalmologic surgical management.