Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal urate excretion in normal man.

T H Steele, R E Rieselbach

    Nephron
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    This study summarizes knowledge on kidney urate excretion. Evidence suggests extensive tubular reabsorption and secretion regulate urate levels in healthy individuals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The history of the University of Wisconsin transplant program.

    Clinical transplants·2008
    Same author

    ACC/AHA Guidelines for Coronary Artery Bypass Graft Surgery: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1991 Guidelines for Coronary Artery Bypass Graft Surgery). American College of Cardiology/American Heart Association.

    Journal of the American College of Cardiology·1999
    Same author

    ACC/AHA guidelines for coronary artery bypass graft surgery: executive summary and recommendations : A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to revise the 1991 guidelines for coronary artery bypass graft surgery).

    Circulation·1999
    Same author

    Hyperuricemic nephropathies.

    Nephron·1999
    Same author

    Renal transplantation in a patient with methylmalonic acidaemia.

    Journal of inherited metabolic disease·1998
    Same author

    The feasibility of consortia for internal medicine graduate medical education: perspectives from a survey of residency directors.

    Academic medicine : journal of the Association of American Medical Colleges·1997
    Same journal

    Expert Commentary of the Recent International Pediatric Nephrology Association IgA Vasculitis Nephritis Guidelines.

    Nephron·2026
    Same journal

    Acute effects of exercise on the nephron index under different conditions in middle-aged males - a preliminary study.

    Nephron·2026
    Same journal

    Lysozyme-Associated Nephropathy in Myeloid Neoplasms: A Clinicopathological and Mass Spectrometric Study of Two Cases.

    Nephron·2026
    Same journal

    Prevalence of COVID-19 Pneumonia and Clinical Characteristics in Hemodialysis Patients During the SARS-CoV-2 Omicron Pandemic.

    Nephron·2026
    Same journal

    Real-World Outcomes of Patients with Monoclonal Gammopathy of Renal Significance.

    Nephron·2026
    Same journal

    Long-Term Therapy with Eculizumab Biosimilar in Patients with Atypical Haemolytic Uraemic Syndrome: Outcomes of a Prospective Observational Study.

    Nephron·2026
    See all related articles

    Area of Science:

    • Nephrology
    • Renal Physiology
    • Urate Metabolism

    Background:

    • Urate excretion is a complex renal process.
    • Understanding intrarenal urate handling is crucial for managing conditions like gout.

    Purpose of the Study:

    • To summarize the current understanding of intrarenal urate excretion control in normal humans.
    • To identify gaps and interpret existing data on urate handling by the kidneys.

    Main Methods:

    • Review and synthesis of existing scientific literature on renal urate transport.
    • Analysis of data related to glomerular filtration, tubular reabsorption, and tubular secretion of urate.

    Main Results:

    • Current evidence supports significant tubular reabsorption of filtered urate.

    Related Experiment Videos

  • Evidence suggests subsequent tubular secretion of urate, followed by partial reabsorption of secreted urate.

    • Conclusions:

    • The regulation of urate excretion is likely achieved through modulation of tubular secretion and/or post-secretory reabsorption.
    • Further research is needed to fully elucidate the mechanisms controlling urate excretion.