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[Diagnostic laparoscopy--a useful tool in abdominal lymphoma]
D Lev-Chelouche1, D Margal, J M Klausner
1Dept. of Surgery B, Tel Aviv-Sourasky Medical Center, Sackler Medical Faculty, Tel Aviv University.
Harefuah
|March 13, 2001
Summary
Diagnostic laparoscopy offers a safe and effective method for diagnosing intra-abdominal lymphoma when percutaneous biopsy is inconclusive. This minimally invasive procedure provides adequate tissue for comprehensive analysis, improving lymphoma diagnosis and treatment planning.
Area of Science:
- Oncology
- Surgical Pathology
- Diagnostic Imaging
Context:
- Percutaneous biopsy guided by computed tomography (CT) or ultrasound (US) is standard for diagnosing intra-abdominal lymphoma.
- Inadequate tissue samples from percutaneous biopsy can hinder specialized analyses like immunophenotyping and cytogenetics.
- Diagnostic laparoscopy has proven successful for gastrointestinal malignancies, suggesting its utility for intra-abdominal lymphomas.
Purpose:
- To evaluate the safety and efficacy of diagnostic laparoscopy for diagnosing intra-abdominal lymphoma.
- To compare laparoscopy with conventional imaging-guided percutaneous biopsy in lymphoma diagnosis.
Summary:
- Fifteen patients with suspected intra-abdominal lymphoma underwent diagnostic laparoscopy.
- Preoperative percutaneous fine-needle aspiration (FNA) was inconclusive in 9 patients.
- Laparoscopy yielded a lymphoma diagnosis in 14 patients (93%) with no mortality or major complications; one false negative was resolved with a second procedure.
Impact:
- Diagnostic laparoscopy is a safe and efficient tool for diagnosing abdominal lymphoma, yielding sufficient tissue for comprehensive analysis.
- This procedure can overcome limitations of percutaneous biopsy, improving diagnostic accuracy and guiding therapeutic decisions.
- The findings support the integration of diagnostic laparoscopy into the workup of suspected intra-abdominal lymphoma.