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Updated: Oct 9, 2026

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
Inhaled nitric oxide for pulmonary hemorrhage due to acute pulmonary vein trauma
P R Vogt1, D Schmidlin, E Bernard
1Clinic for Cardiovascular Surgery, and University Hospital Zurich, Switzerland. paul.vogt@chi.usz.ch
Abstract:
A 57-year-old man with a history of prosthetic aortic valve and supracoronary ascending aortic replacement presented with a 9.8 cm Sinuses of Valsalvae aneurysm ruptured into the left upper pulmonary vein leading to massive pulmonary hemorrhage due to acute rupture of small pulmonary veins. Prosthetic graft replacement of the aneurysm and reconstruction of the atrial roof and left upper pulmonary vein was performed. Inhaled nitric oxide reversed treatment-refractory hypoxemia following massive small pulmonary vein trauma.
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