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Published on: February 23, 2014
[A case of mumps pneumonia complicated with acute respiratory failure]
K Fujita1, S Akutgawa, S Ikeda
1Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-City, Osaka, Japan.
Abstract:
A 38-year-old male with swollen parotid glands was admitted to our hospital with dyspnea on effort. Positive serum IgM antibody for mumps supported a diagnosis of mumps. Computed tomography (CT) scan showed a ground-glass appearance in both lower lungs. On the third day of hospitalization, bronchoalveolar lavage demonstrated an elevation of both the total cell (2.0 x 10(6)/cc) and the lymphocyte count (83%), as well as a decrease of the CD 4+/CD 8+ ratio (0.4). Bronchial biopsy specimens revealed infiltration of lymphocytes in both the bronchiolar walls and the alveolar septa. These data were suggestive of mumps pneumonia. The patients suffered acute respiratory failure on the seventh day of hospitalization, which improved after 3 days of high-dose methyl prednisolone therapy. This is the first report of adult mumps pneumonia in Japan. As a result of the examination of the bronchoalveolar lavage and a bronchial biopsy of viral pneumonia which had been reported in the past, mumps pneumonia was a corresponding opinion to other viral pneumonia.
Insights
This case report details adult mumps pneumonia, a rare complication of mumps virus infection. Prompt diagnosis and high-dose methylprednisolone therapy were crucial for recovery from acute respiratory failure.
Area of Science:
- Infectious Diseases
- Pulmonology
- Virology
Background:
- Mumps virus typically causes parotitis but can lead to severe complications.
- Adult mumps pneumonia is infrequently reported, especially in Japan.
Observation:
- A 38-year-old male presented with dyspnea and swollen parotid glands, confirmed as mumps.
- Computed tomography revealed ground-glass opacities in the lungs.
- Bronchoalveolar lavage showed elevated lymphocytes and a decreased CD4+/CD8+ ratio.
Findings:
- Bronchial biopsy confirmed lymphocytic infiltration, indicative of viral pneumonia.
- The patient developed acute respiratory failure but improved with methylprednisolone.
- This case represents the first documented instance of adult mumps pneumonia in Japan.
Implications:
- Highlights mumps pneumonia as a differential diagnosis in adults with respiratory symptoms and mumps.
- Suggests high-dose corticosteroids may be beneficial in managing severe mumps pneumonia.
- Emphasizes the need for continued surveillance and research into mumps virus complications.
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