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Related Experiment Videos

Multicentric lymphosarcoma in a dog with multiple-site skeletal involvement.

R S Dhaliwal1, A L Reed, B E Kitchell

  • 1All-Care Animal Referral Center, St Fountain Valley, CA 92708, USA.

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
|March 14, 2001
PubMed
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This report details a rare case of canine lymphosarcoma (LSA) presenting as sudden tetraparesis and widespread bone lesions. The aggressive nature of this bone cancer led to a poor prognosis and limited treatment options.

Area of Science:

  • Veterinary Medicine
  • Oncology
  • Canine Pathology

Background:

  • Lymphosarcoma (LSA) is a common canine malignancy.
  • Extranodal LSA, particularly involving bone, is rare.
  • Unusual presentations pose diagnostic and therapeutic challenges.

Observation:

  • A 9-year-old Golden Retriever presented with acute tetraparesis.
  • Radiographs revealed multiple bone lesions, and histology confirmed lymphosarcoma with diffuse skeletal and soft tissue involvement.

Findings:

  • Malignant lymphosarcoma of the bone is an uncommon extranodal clinicopathologic entity.
  • The canine patient showed poor response to medical management.
  • The case highlights the diagnostic and therapeutic difficulties associated with skeletal LSA.

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Implications:

  • This case underscores the rarity and aggressive nature of extranodal lymphosarcoma in canine bone.
  • Further research is needed to determine optimal diagnostic and therapeutic strategies for this rare condition.
  • Veterinary oncologists should consider skeletal LSA in cases of unexplained tetraparesis and bone lesions in dogs.