Multicentric lymphosarcoma in a dog with multiple-site skeletal involvement

In this report the authors describe an unusual clinical presentation of lymphosarcoma (LSA) in a dog. A 9-year-old, neutered male, Golden Retriever was presented with a primary complaint of sudden onset of tetraparesis. Routine survey radiographs revealed multiple-site bony lesions and the histology revealed a diagnosis of LSA with diffuse skeletal and soft tissue involvement. The dog responded poorly to medical management and was euthanized on day two due to poor prognosis. Malignant LSA of the bone is a rare extranodal clinicopathologic entity and presents both a diagnostic and therapeutic hurdle. Reports of this kind are sparse and currently no optimal treatment for this entity has been determined.