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Multicentric lymphosarcoma in a dog with multiple-site skeletal involvement.
R S Dhaliwal1, A L Reed, B E Kitchell
1All-Care Animal Referral Center, St Fountain Valley, CA 92708, USA.
Summary
This report details a rare case of canine lymphosarcoma (LSA) presenting as sudden tetraparesis and widespread bone lesions. The aggressive nature of this bone cancer led to a poor prognosis and limited treatment options.
Area of Science:
- Veterinary Medicine
- Oncology
- Canine Pathology
Background:
- Lymphosarcoma (LSA) is a common canine malignancy.
- Extranodal LSA, particularly involving bone, is rare.
- Unusual presentations pose diagnostic and therapeutic challenges.
Observation:
- A 9-year-old Golden Retriever presented with acute tetraparesis.
- Radiographs revealed multiple bone lesions, and histology confirmed lymphosarcoma with diffuse skeletal and soft tissue involvement.
Findings:
- Malignant lymphosarcoma of the bone is an uncommon extranodal clinicopathologic entity.
- The canine patient showed poor response to medical management.
- The case highlights the diagnostic and therapeutic difficulties associated with skeletal LSA.
Implications:
- This case underscores the rarity and aggressive nature of extranodal lymphosarcoma in canine bone.
- Further research is needed to determine optimal diagnostic and therapeutic strategies for this rare condition.
- Veterinary oncologists should consider skeletal LSA in cases of unexplained tetraparesis and bone lesions in dogs.