Related Experiment Videos

Subunit-dependent modulation of neuronal nicotinic receptors by zinc

B Hsiao¹, D Dweck, C W Luetje

¹Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, Florida 33101, USA.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

|March 14, 2001

Abstract:

We examined the effect of zinc on rat neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes as simple heteromers of alpha2, alpha3, or alpha4 and beta2 or beta4. Coapplication of zinc with low concentrations of acetylcholine (

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

High incidence of false-positive PET scans in patients with aggressive non-Hodgkin's lymphoma treated with rituximab-containing regimens.

Annals of oncology : official journal of the European Society for Medical Oncology·2008

Determinants of agonist binding affinity on neuronal nicotinic receptor beta subunits.

The Journal of pharmacology and experimental therapeutics·2001

Activity-dependent modulation of rod photoreceptor cyclic nucleotide-gated channels mediated by phosphorylation of a specific tyrosine residue.

The Journal of neuroscience : the official journal of the Society for Neuroscience·1999

Neuronal nicotinic receptor beta2 and beta4 subunits confer large differences in agonist binding affinity.

Molecular pharmacology·1998

Differential roles for disulfide bonds in the structural integrity and biological activity of kappa-Bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist.

Biochemistry·1998

Glycosylation within the cysteine loop and six residues near conserved Cys192/Cys193 are determinants of neuronal bungarotoxin sensitivity on the neuronal nicotinic receptor alpha3 subunit.

Molecular pharmacology·1998

See all related articles