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Polymeric controlled drug-delivery systems: perspective issues and opportunities.

M N Kumar1, N Kumar

  • 1Department of Chemistry, University of Roorkee, Roorkee-247 667, India. rmje0@pop.uky.edu

Drug Development and Industrial Pharmacy
|March 15, 2001
PubMed
Summary

Recent advances in drug-delivery systems (DDS) focus on targeted delivery to disease sites using pH-responsive polymers. This review compiles new technologies and future prospects for controlled drug release.

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Area of Science:

  • Applied Polymer Science
  • Biomedical Engineering
  • Materials Science

Background:

  • Drug-delivery systems (DDS) are crucial for targeted disease treatment.
  • Achieving sufficient drug dosage at lesions requires effective drug carriers.
  • pH-responsive polymers offer potential for controlled drug release.

Purpose of the Study:

  • To review recent advancements in controlled drug-delivery technology.
  • To discuss future prospects in the field of drug delivery.
  • To provide a comprehensive resource for researchers and beginners.

Main Methods:

  • Review of current scientific literature on drug-delivery systems.
  • Analysis of emerging technologies, particularly pH-responsive polymers.
  • Compilation of recent developments and future research directions.

Main Results:

  • Significant progress in DDS, especially in targeted drug delivery.
  • Exploration of polymers that respond to external pH levels for drug release.
  • Development and testing of novel drug delivery technologies.

Conclusions:

  • Controlled drug-delivery technology is rapidly evolving.
  • pH-responsive polymers represent a promising area for future research.
  • This review consolidates current knowledge and highlights future opportunities in applied polymer science for drug delivery.