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Penicillin-resistant Streptococcus pneumoniae endocarditis: a case report and review
1Division of Infectious Diseases, Department of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.
Summary
Penicillin-resistant Streptococcus pneumoniae endocarditis is rare but emerging. This case highlights successful treatment of bivalvular PRSP endocarditis with vancomycin and trovafloxacin, underscoring treatment challenges.
Area of Science:
- Cardiology
- Infectious Diseases
- Microbiology
Background:
- Streptococcus pneumoniae is an uncommon cause of endocarditis, especially in the postantibiotic era.
- The rise of antibiotic-resistant Pneumococcus strains has led to isolated cases of penicillin-resistant S. pneumoniae (PRSP) endocarditis.
Observation:
- This report details a rare instance of bivalvular endocarditis caused by PRSP.
- The patient's infection involved multiple heart valves, complicating the clinical picture.
Findings:
- The case demonstrates successful management of PRSP endocarditis using a combination of vancomycin and trovafloxacin.
- Literature review indicates a need for effective therapeutic strategies against resistant pneumococcal endocarditis.
Implications:
- This case contributes to understanding the clinical presentation and treatment of antibiotic-resistant bacterial endocarditis.
- Further research into optimal treatment regimens for PRSP endocarditis is warranted given the increasing resistance patterns.