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The pharmacist's ability to use bioavailability data.

J D Cronk, R B Williams, W E Moore

    American Journal of Hospital Pharmacy
    |January 1, 1975
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    Pharmacists effectively evaluated drug products using analytical, dissolution, blood level, and cost data. However, their assessment of urinary excretion data was inadequate compared to expert evaluations.

    Area of Science:

    • Pharmacology
    • Pharmaceutical Sciences
    • Drug Evaluation

    Background:

    • Pharmacists play a crucial role in drug product evaluation.
    • Assessing the utility of various data types in pharmacist decision-making is essential.

    Purpose of the Study:

    • To investigate pharmacists' ability to interpret and utilize diverse data sets for drug product evaluation.
    • To compare pharmacist performance against an expert panel in data interpretation.

    Main Methods:

    • A questionnaire-based study involving 19 pharmacists.
    • Pharmacists evaluated four antibiotic brands using provided analytical, dissolution, blood level, excretion, and cost data.
    • Responses were compared against an expert panel's evaluations.

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    Main Results:

    • Pharmacists demonstrated adequate proficiency in evaluating analytical, dissolution, blood level, and cost data.
    • A significant deficiency was observed in pharmacists' evaluation of urinary excretion data.
    • Expert panel comparison highlighted specific areas for pharmacist improvement.

    Conclusions:

    • Pharmacists are generally capable of using common drug evaluation data but require further training in interpreting complex pharmacokinetic parameters like urinary excretion.
    • Enhancing pharmacists' skills in utilizing all available drug data can improve therapeutic decision-making and patient outcomes.