Related Experiment Video
Updated: Aug 4, 2026
09:30
Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
Facial soft-tissue augmentation with allogeneic human tissue collagen matrix (Dermalogen and Dermaplant)
Clinics in Plastic Surgery
|March 16, 2001
Summary
Human collagen tissue matrix, like Dermalogen, effectively addresses facial aging signs such as volume loss and wrinkles. Long-term results depend on various factors, with repeat treatments potentially needed for sustained effects.
Area of Science:
- Plastic Surgery
- Dermatology
- Biomaterials Science
Background:
- Facial rejuvenation relies on soft-tissue augmentation to restore volume and correct contour defects.
- Human collagen tissue matrix presents a physiologically compatible option for addressing dermal volume depletion and facial rhytides.
Purpose of the Study:
- To evaluate the efficacy of human collagen tissue matrix, specifically Dermalogen and Dermaplant, for facial soft-tissue augmentation.
- To compare the natural effects and persistence of human collagen matrix with other injectable dermal agents.
Main Methods:
- Utilized human collagen tissue matrix (Dermalogen, Dermaplant) for facial rejuvenation procedures.
- Compared clinical results with other injectable dermal agents, acellular dermal grafts, and alloplastic grafts.
Main Results:
- Dermalogen demonstrated natural effects comparable to other injectable dermal agents for facial rejuvenation.
- Dermaplant is effective for nasolabial fold and lip augmentation, as well as secondary eyelid and nasal reconstruction.
Conclusions:
- Human collagen tissue matrix is a viable option for various facial soft-tissue augmentation and reconstruction needs.
- Long-term persistence of human collagen matrix varies by facial region, technique, and volume; repeat dosing may be necessary.
- Further clinical studies are needed to establish long-term persistence and comparative results against other graft materials.
