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Preparing Adherent Cells for X-ray Fluorescence Imaging by Chemical Fixation
Published on: March 12, 2015
Behind the discovery of "Nissenbaum's fixative"
1Department of Medicine, Jersey City Medical Center, New Jersey 07304, USA. nissenfix@home.com
The Journal of Eukaryotic Microbiology
|March 16, 2001
Summary
Nissenbaum
Area of Science:
- Histotechnology
- Biomedical Research
Background:
- Recounts the serendipitous discovery of Nissenbaum's Fixative by an undergraduate biology major in the early 1950s.
- Details the conception and initial development of this histological fixative.
Discussion:
- Explores the evolution and history of Nissenbaum's Fixative over 47 years.
- Highlights various applications and modifications, including those not in the original publication.
Key Insights:
- Documents the long-term utility and adaptability of Nissenbaum's Fixative in histology.
- Provides historical context for a specific histological preparation method.
Outlook:
- Suggests potential for further modifications or applications of Nissenbaum's Fixative.
- Connects the fixative's history to the author's broader medical career.
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