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Updated: Aug 12, 2026
09:31
Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Effects of positive end-expiratory pressure on diaphragm function
J D Pierce1, C L Perkins, K J Rhea
1University of Kansas, School of Nursing, 3901 Rainbow Blvd, Kansas City, KS 66160-7502, USA.
Summary
Post-anesthesia care unit (PACU) patients on mechanical ventilation can benefit from understanding positive end-expiratory pressure (PEEP). This review explores PEEP
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Respiratory Physiology
Background:
- Mechanical ventilation is common for PACU patients.
- Increasing patient acuity necessitates higher PEEP levels.
- Understanding diaphragm function is crucial for weaning.
Purpose of the Study:
- To review positive end-expiratory pressure (PEEP) as a mechanical ventilation mode.
- To examine the relationship between PEEP and diaphragmatic performance.
- To discuss the physiological effects of PEEP.
Main Methods:
- Literature review of PEEP and diaphragmatic function.
- Analysis of physiological effects of PEEP.
- Synthesis of current knowledge on PEEP in PACU settings.
Main Results:
- PEEP influences diaphragmatic performance.
- Understanding PEEP-ventilator interactions is key for PACU nurses.
- Physiological effects of PEEP vary.
Conclusions:
- Knowledge of PEEP and diaphragm function aids PACU patient management.
- Effective weaning requires understanding PEEP's impact on the diaphragm.
- Further research into PEEP optimization is warranted.
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