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Patent review: therapeutic applications for antisense oligonucleotides 1999-2000
1CRC Centre for Cancer Therapeutics, Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK. rosanne@icr.ac.uk
Over 200 patents on antisense sequences were published recently. This review details 30 patents claiming therapeutic applications, categorized by disease area for a comprehensive overview of antisense research.
Area of Science:
- Biotechnology
- Molecular Biology
- Drug Discovery
Background:
- Antisense technology represents a significant advancement in targeted therapeutics.
- A surge in patent filings indicates rapid development and investment in antisense-based drug discovery.
- Understanding the therapeutic landscape of antisense sequences is crucial for researchers and developers.
Purpose of the Study:
- To review and classify recently patented antisense sequences with claimed therapeutic applications.
- To provide an overview of major research areas within antisense technology.
- To highlight key developments in antibacterial, antiviral, inflammation, cardiovascular, apoptosis, and anticancer applications.
Main Methods:
- Systematic review of over 200 patents published within the last year.
- Filtering patents to include only those claiming specific therapeutic applications.
- Classification of selected patents into distinct therapeutic categories.
Main Results:
- Identified 30 patents with claimed therapeutic applications for antisense sequences.
- Categorized these patents into key areas: antibacterial, antiviral, inflammation, cardiovascular, apoptosis, and anticancer.
- Demonstrated a broad application scope for antisense technology across various diseases.
Conclusions:
- Antisense technology is a rapidly evolving field with diverse therapeutic potential.
- The reviewed patents highlight significant progress in developing antisense-based treatments for major diseases.
- Further research and development in antisense sequences are expected to yield novel therapeutic strategies.
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