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DNA vaccines against tuberculosis
1National Institute for Medical Research, Ridgeway, Mill Hill, London, NW7 1AA, UK. dlowrie@nimr.mrc.ac.uk
Current Opinion in Molecular Therapeutics
|March 16, 2001
Abstract:
Application of the DNA vaccine approach to tuberculosis in laboratory animals is helping to clarify the immunological mechanisms underlying protective immunity. Unexpectedly, it has also indicated clear potential for clinical application. This review looks at the implication of recent advances for the development of practical TB vaccines.