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Unraveling the mechanisms by which heat shock proteins activate the immune system
1Center for Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. dpp60@mit.edu
Current Opinion in Molecular Therapeutics
|March 16, 2001
Abstract:
A role for heat shock proteins in eliciting CD8 cytotoxic T-lymphocyte (CTL) responses in the absence of exogenous adjuvants has been documented for some time. Only recently, however, has the mechanism by which these molecules are able to elicit such responses begun to be elucidated.