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Updated: Jul 31, 2026
09:52
Probing The Structure And Dynamics Of Nucleosomes Using Atomic Force Microscopy Imaging
Published on: January 31, 2019
Higher-order structure of chromatin and chromosomes
1Biology Department, University of Massachusetts, Amherst 01003, USA. chris@bio.umass.edu
Current Opinion in Genetics & Development
|March 16, 2001
Abstract:
The linear array of nucleosomes that comprises the primary structure of chromatin is folded and condensed to varying degrees in nuclei and chromosomes forming 'higher order structures'. We discuss the recent findings from novel experimental approaches that have yielded significant new information on the different hierarchical levels of chromatin folding and their functional significance.
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