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Characterization of cross-reacting allergens in mango fruit
A Paschke1, H Kinder, K Zunker
1University of Hamburg, Institute of Biochemistry and Food Chemistry, Germany.
Background:
Allergic reactions to mango fruit have become increasingly important. A cross-reaction between mango fruit, various other foods, and respiratory allergens has been assumed but not investigated until now.
Methods:
The sera of nine patients were used to characterize cross-reacting allergens in mango fruits by EAST inhibition and immunoblot inhibition.
Results And Conclusions:
EAST inhibition and immunoblot inhibition demonstrated that cross-reactions between mango fruits, mugwort pollen, birch pollen, celery, and carrot are based on allergens related to Bet v 1 and Art v 1, the major allergens of birch and mugwort pollen, respectively.
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