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Reducing medication regimen complexity: a controlled trial.

A J Muir1, L L Sanders, W E Wilkinson

  • 1Division of Gastroenterology, Duke University Medical Center, Durham, NC 27710, USA. muir0002@mc.duke.edu

Journal of General Internal Medicine
|March 17, 2001
PubMed
Summary
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A simple medication grid intervention for physicians significantly reduced medication regimen complexity and doses per day in patients taking multiple medications. This visual aid helped address polypharmacy effectively.

Area of Science:

  • Internal Medicine
  • Clinical Pharmacy
  • Health Services Research

Background:

  • Polypharmacy, the use of multiple medications, is common in hospitalized patients.
  • Managing complex medication regimens increases the risk of adverse events and healthcare costs.
  • Physicians may benefit from tools to simplify medication management.

Purpose of the Study:

  • To evaluate the effectiveness of a visual intervention, a medication grid, in reducing medication regimen complexity.
  • To assess the impact of the intervention on the number of medications and daily doses.
  • To determine if physicians address polypharmacy when presented with simplified medication information.

Main Methods:

  • A nonrandomized, controlled trial was conducted at a Veterans Affairs medical center.

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  • Eight hundred thirty-six patients on at least 5 medications were included.
  • Physician teams received a medication grid detailing patient medications and administration times for intervention patients.

    • Main Results:

    • The intervention group saw a decrease of 0.92 medications per patient, while the control group increased by 1.65 (P <.001).
    • Mean daily doses decreased by 2.47 per patient in the intervention group, compared to an increase of 3.83 in the control group (P <.001).
    • The medication grid intervention demonstrated a significant impact on reducing medication complexity.

    Conclusions:

    • A simple visual intervention, the medication grid, effectively reduced medication regimen complexity.
    • Physicians were able to address polypharmacy when the issue was visually highlighted.
    • This intervention offers a practical approach to managing complex medication regimens in inpatient settings.