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Visceral pain in humans: lessons from animals
1Department of Veterinary Clinical Sciences, Ohio State University Veterinary Hospital, 601 Vernon L. Tharp Street, Columbus, OH 43210, USA. buffington.1@osu.edu
Current Pain and Headache Reports
|March 17, 2001
Summary
Animal studies enhance our understanding of pain and nociception, differentiating sensory inputs and exploring genetic influences. Research on animal pain syndromes informs human pain management, emphasizing ethical animal care.
Area of Science:
- Neuroscience
- Veterinary Medicine
- Pain Research
Background:
- Animal models are crucial for understanding nociception and pain.
- Distinguishing between somatic and visceral pain pathways is essential.
- Genetic and environmental factors influence pain responses.
Purpose of the Study:
- To review the contribution of animal studies to pain research.
- To highlight the pathways involved in nociception.
- To discuss the ethical considerations of using animals in pain research.
Main Methods:
- Literature review of animal studies on nociception and pain.
- Analysis of research differentiating somatic and visceral pain.
- Examination of genetic and environmental influences on pain perception.
Main Results:
- Animal studies have significantly advanced the understanding of pain transduction, transmission, perception, and modulation.
- Research has clarified the differences between somatic and visceral nociceptive input.
- Naturally occurring animal pain syndromes offer insights into human conditions.
Conclusions:
- Animal research is vital for advancing pain science and management in both animals and humans.
- Ethical treatment and humane care are paramount when using animals in pain studies.
- Continued investigation into nociception in animals will yield further benefits for comparative pain research.