Related Experiment Video
Updated: Aug 18, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Water in normal muscle and muscle with a tumor
Abstract:
The total water content, the amount of non-freezable water, and the Na-+ and K-+ contents in the gastrocnemius muscle of albino mice with and without a solid tumor were determined. The spin-lattice relaxation time (T1) for the water protons in the two kinds of muscle were measured at six resonance frequencies ranging from 4.5 to 60 MHz over the temperature range +37 to minus 65 degrees C. Quantitatively calculated T1 values are given. The difference in T1 for the two types of muscle at temperatures above minus 5 degrees C is attributed to the difference in the distribution ratio of water between hydration and free states, and bears no direct relation to the concentration of Na-+.
Related Concept Videos
The Tumor Microenvironment
Satellite Stem Cells and Muscular Dystrophy
Microscopic Anatomy of Skeletal Muscles
The muscle sarcolemma is a plasma membrane enclosing each muscle cell that conducts electrical signals called action potentials. The sarcolemma extends into the cell to form T-tubules, ensuring the neural impulses are uniformly distributed across the entire muscle...
Structure of Cardiac Muscles
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
Alterations in Muscle Tone ll
Alterations in Muscle Tone lll

