Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetic disease since 1945.

M S Lindee1

  • 1School of Arts and Sciences, Department of History and Sociology of Science, Logan Hall, Suite 303, 249 South 36th Street, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6304, USA. mlindee@mail.sas.upenn.edu

Nature Reviews. Genetics
|March 17, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The repatriation of atomic bomb victim body parts to Japan: natural objects and diplomacy.

Osiris·2001
Same author

Media portrayals of genetics.

American journal of human genetics·1998
Same author

Cloning in the popular imagination.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·1998
Same author

The revival of eugenics in American popular culture.

Journal of the American Medical Women's Association (1972)·1997
Same author

The ELSI hypothesis.

Isis; an international review devoted to the history of science and its cultural influences·1994
Same author

Atonement: understanding the no-treatment policy of the Atomic Bomb Casualty Commission.

Bulletin of the history of medicine·1994

Genetic disease understanding shifted dramatically, moving from rare to a key factor in most human illnesses. This change occurred between the 1970s and 1990s, impacting medical perspectives on hereditary conditions.

Area of Science:

  • Medical Genetics
  • Human Pathology
  • History of Medicine

Background:

  • Genetic diseases were historically viewed as rare and clinically insignificant before the 1970s.
  • Physicians' perspectives on the role of genetics in disease underwent a significant transformation.
  • The understanding of hereditary conditions evolved considerably over a few decades.

Observation:

  • By the 1990s, genetic factors became widely accepted as crucial in nearly all human diseases.
  • The shift in perspective was driven by advancements and changing paradigms in medical science.
  • Case studies of familial dysautonomia and phenylketonuria illustrate this evolving understanding.

Findings:

  • The perception of genetic disease prevalence and importance changed profoundly from the 1970s to the 1990s.

Related Experiment Videos

  • This transformation highlights the dynamic nature of scientific understanding in medicine.
  • The increasing recognition of genes' role in disease has reshaped clinical practice and research.

    • Implications:

    • The re-evaluation of genetic disease has profound implications for understanding and treating a wide range of human pathologies.
    • This historical shift underscores the importance of ongoing research in genetics and its clinical applications.
    • Future medical approaches increasingly integrate genetic insights for personalized and effective healthcare solutions.