Related Experiment Videos
[Imaging of angiogenesis]
C Bremer1, A A Bogdanov, R Weissleder
1Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA.
Abstract:
Angiogenesis of tumors has gained tremendous attention in the research community over the last years. Novel anti-angiogenic treatment protocols are currently in various phases of clinical testing. Thus, the major challenge for Radiological diagnostics is to develop imaging methods which reliably measure the angiogenic tumor burden as well as tumor response to anti-angiogenic treatment in vivo. This article intends to provide a brief overview of imaging strategies for angiogenesis and anti-angiogenic treatment.
Insights
Radiological diagnostics face challenges in measuring tumor angiogenesis and treatment response. This article reviews imaging strategies to assess tumor angiogenesis and response to anti-angiogenic therapies in vivo.
Area of Science:
- Oncology
- Radiology
- Molecular Imaging
Context:
- Tumor angiogenesis is a critical hallmark of cancer.
- Novel anti-angiogenic therapies are advancing rapidly through clinical trials.
- Accurate assessment of tumor angiogenesis and treatment efficacy is crucial.
Purpose:
- To provide an overview of current imaging strategies for angiogenesis.
- To discuss methods for evaluating tumor response to anti-angiogenic treatments.
- To highlight the role of radiological diagnostics in cancer therapy.
Summary:
- This review covers imaging techniques for visualizing and quantifying tumor angiogenesis.
- It explores how these methods can monitor tumor burden and response to anti-angiogenic drugs.
- Focus is placed on in vivo imaging for clinical applications.
Impact:
- Improved diagnostic capabilities for assessing tumor angiogenesis.
- Enhanced ability to monitor and personalize anti-angiogenic cancer treatments.
- Facilitating the clinical translation of novel anti-angiogenic therapies.