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Updated: Oct 9, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
[Heparin induced thrombocytopenia, left ventricular thrombus and cerebral embolism during an acute myocardial
1Medizinische Klinik I, Allgemeine Innere Medizin, Gastroenterologie, Diabetologie, Stoffwechsel und Ernährung, Evangelisches und Johanniter-Klinikum Duisburg/Dinslaken/Oberhausen. jakdaniels@t-online.de
History And Clinical Findings:
A 58-year-old male patient was admitted to the emergency room after reanimation in hypotensive shock, under sedation and respiration.
Investigations:
The cardiac laboratory markers were within normal limits. The ECG demonstrated a sinustachycardia with typical infarction signs. The echocardiogram showed a hypokinesia of the cardiac apex. DIAGNOSTICS, TREATMENT AND COURSE: Acute myocardial infarction was treated with a systemic rt-PA lysis. The course was complicated by: confirmed heparin-induced thrombocytopenia, left ventricular thrombus and a cerebral embolism. After multiple adaptations of the anticoagulation regimen, the patient was discharged in a good condition without major neurologic deficits.
Conclusion:
With a careful anticoagulation regimen it is possible to achieve a successful outcome in major complications such as heparin-induced thrombocytopenia, left ventricular thrombus and cerebral embolism.
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