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Updated: Sep 14, 2026

Photo-Induced Cross-Linking of Unmodified Proteins (PICUP) Applied to Amyloidogenic Peptides
Published on: January 12, 2009
[Oligomeric proteins: modulation of UV-sensitivity and characteristics of photochemical transformations]
V G Artiukhov1, O V Basharina, G A Vashanov
1Voronezh State University, 394693 Russia. bsbf188@main.vsu.ru
Abstract:
The results of our research devoted to the study of photophysical and photochemical transformations of some compound proteins of oxidative, antioxidant, transport and immune systems of an organism under conditions of different microenvironment (presence of chemical modificators, the change of pH, temperature, doses and spectral composition of ultraviolet irradiation) have been analyzed. Methods and the degree of modulation of UV-sensitivity of proteins of the mentioned systems have been discussed. Conditions, on which the used chemical agents show photoprotective and photosensitizing effect on protein molecules, have been found.
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