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Styryllactones from the rhizomes of Goniothalamus griffithii
Y J Zhang1, G X Zhou, R Y Chen
1Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
Journal of Asian Natural Products Research
|March 20, 2001
Abstract:
Three new styryl-lactones 8-acetylgoniofufurone(1), 7-acetylgonio-pypyrone(3), and 5-acetylgoniopypyrone(4), along with ten known compounds, goniofufurone(2), goniopypyrone(5), goniothalamin, goniothalenol, (+)-isoaltholactone, goniodiol, 7-acetylgoniodiol, goniotriol, 8-acetylgoniotriol, 9-deoxygoniopypyrone were isolated from the rhizomes of Goniothalamus griffithii Hook f. et. Thoms. Their structures were elucidated by IR, MS, NMR spectra and chemical evidence. All compounds showed cytotoxic activities against human cancer cell lines.