Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Posterior subcapsular and nuclear cataract after vitrectomy.

J D Hsuan1, N A Brown, A J Bron

  • 1Oxford Eye Hospital, Oxford, UK.

Journal of Cataract and Refractive Surgery
|March 20, 2001
PubMed
Summary

Pars plana vitrectomy with tamponade can cause transient posterior subcapsular cataract (PSC) and accelerated nuclear opacification. These lens changes, particularly PSC, are common after vitrectomy surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Spectrum and Genetics of Ocular Manifestations in Muscle Eye Brain Disease: A Literature Review.

Seminars in ophthalmology·2026
Same author

Multi-omics characterization of microbial and metabolite profiles of Jeevamrit and Ghanjeevamrit cow-based bioformulations used in sustainable agriculture.

Scientific reports·2026
Same author

Metagenomic insights reveal the impact of natural farming on soil nutrients, enzyme activities, microbial communities, and yield in turmeric cultivation.

BMC plant biology·2025
Same author

Spontaneous retinal reattachment and novel vitreoretinal phenotype in muscle eye brain disease determined by fundus multimodal imaging.

European journal of ophthalmology·2025
Same author

Variability of retinopathy consequent upon novel mutations in LAMA1.

Ophthalmic genetics·2022
Same author

Accuracy of scleral transillumination techniques to identify infant ciliary body for sclerostomy and intravitreal injections.

Clinical & experimental ophthalmology·2018

Area of Science:

  • Ophthalmology
  • Surgical Outcomes
  • Lens Biology

Background:

  • Pars plana vitrectomy is a common surgical procedure for various retinal conditions.
  • The impact of vitrectomy, especially with intraocular tamponade, on the native lens is a significant clinical concern.
  • Understanding post-surgical lens changes is crucial for managing patient vision and planning subsequent interventions.

Purpose of the Study:

  • To investigate the morphological alterations in the lens following pars plana vitrectomy.
  • To track the temporal progression of these lens changes, including cataract development.
  • To differentiate changes associated with tamponade agents versus vitrectomy alone.

Main Methods:

  • Prospective study of 33 phakic patients undergoing pars plana vitrectomy.

Related Experiment Videos

  • Quantification of cataract using clinical grading and Scheimpflug imaging.
  • Slitlamp biomicroscopy and photography for morphological documentation.

    • Main Results:

    • A transient posterior subcapsular cataract (PSC) occurred in 89% of tamponade patients within 24 hours.
    • Nuclear opacity developed in 61% of tamponade patients and 50% of non-tamponade patients.
    • Cataract surgery was required in 67% of tamponade cases versus 18% of non-tamponade cases after follow-up.

    Conclusions:

    • Vitrectomy with tamponade induces a distinct, transient PSC post-surgery, suggesting fluid balance disruption.
    • While acute PSC changes may resolve, they are followed by accelerated nuclear opacification.
    • Tamponade use significantly increases the likelihood of both immediate and long-term cataract development requiring surgery.