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Incidental parathyroidectomy during thyroid surgery does not cause transient symptomatic hypocalcemia.
A R Sasson1, J F Pingpank, R W Wetherington
1Head and Neck Surgery Section, Fox Chase Cancer Center, 7701 Burholme Ave, Philadelphia, PA 19111, USA.
Archives of Otolaryngology--Head & Neck Surgery
|March 20, 2001
Summary
Unintended parathyroidectomy during thyroid surgery is common but does not cause symptomatic hypocalcemia. Modified radical neck dissection increases the risk of this incidental parathyroidectomy.
Area of Science:
- Endocrine Surgery
- Surgical Pathology
- Thyroid Cancer Management
Background:
- Incidental parathyroidectomy during thyroid surgery is a recognized complication.
- The association between incidental parathyroidectomy and postoperative hypocalcemia requires further clarification.
Purpose of the Study:
- To determine risk factors for incidental parathyroidectomy.
- To assess the relationship between incidental parathyroidectomy and symptomatic postoperative hypocalcemia.
Main Methods:
- Retrospective analysis of 141 thyroid surgery cases.
- Review of pathology reports for parathyroid tissue in resected specimens.
- Collection of data on patient demographics, diagnoses, surgical details, and complications.
Main Results:
- Incidental parathyroidectomy occurred in 15% of cases, with parathyroid tissue found intrathyroidal, extracapsular, and in the central node compartment.
- Modified radical neck dissection was associated with an increased risk of incidental parathyroidectomy (P=.05).
- Total thyroidectomy was identified as a risk factor for postoperative hypocalcemia (P=.008), while incidental parathyroidectomy was not (P=.99).
Conclusions:
- Unintended parathyroidectomy is not uncommon but does not correlate with symptomatic postoperative hypocalcemia.
- Modified radical neck dissection may elevate the risk of incidental parathyroidectomy.
- Surgical technique modifications are unlikely to significantly reduce the risk due to the prevalence of intrathyroidal parathyroid tissue.