[Problems with therapy for renovascular hypertension in Takayasu's arteritis--on the basis of two cases]

Takayasu's arteritis is non-specific vasculitis, affecting aorta and its main branches. Renal involvement is usually manifested by renovascular hypertension followed by ischemic nephropathy. Early start of immunosuppressive treatment can substantially improve prognosis and delay progress of dangerous organic complications. On the basis of two cases of Takayasu's arteritis with renal involvement, we paid the attention to progressive nature of disease with renovascular hypertension, requiring corrective operation of renal arteries, despite intensive immunosuppressive treatment.