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Spontaneous remission of cyclic neutropenia during pregnancy. A case report
T Kimura1, K Takakura, T Nakagawa
1Department of Obstetrics and Gynecology, Shiga University of Medical Sciences, Seta, Ohtsu 520-2192, Japan. hqgyne@belle.shiga-med.ac.jp
Background:
Cyclic neutropenia is characterized by regularly recurring episodes of neutropenia. It has been reported that pregnancy often has a mitigating effect on the symptoms. However, there have been no detailed studies on changes in the neutrophil count before, during and after pregnancy.
Case:
A 24-year-old woman with cyclic neutropenia had a successful pregnancy, during which her symptoms improved spontaneously, with decreased severity. The disease recurred soon after pregnancy, and cyclic neutropenia was inherited by the child.
Conclusion:
Cyclic neutropenia may follow a favorable course during pregnancy, with decreased severity, but postpartum maternal and neonatal complications can occur.