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Female genital tuberculosis revisted
R N Qureshi1, S Samad, R Hamid
1Department of Obstetrics and Gynaecology, Aga Khan Univeristy Hospital, Karachi.
JPMA. the Journal of the Pakistan Medical Association
|March 21, 2001
Summary
Genital tuberculosis commonly presents as infertility or abdominal pain in women aged 25-45. Early diagnosis and nine-month antituberculous therapy are crucial, though successful pregnancies remain rare.
Area of Science:
- Gynecology
- Infectious Diseases
- Reproductive Medicine
Background:
- Genital tuberculosis (GTB) is a significant cause of female infertility, particularly in endemic regions.
- Understanding the clinical presentation and diagnostic challenges of GTB is essential for timely intervention.
Purpose of the Study:
- To evaluate the clinical manifestations of genital tuberculosis in women.
- To review diagnostic approaches and treatment strategies for GTB.
- To assess treatment outcomes, including pregnancy rates.
Main Methods:
- A retrospective case review was conducted at Aga Khan University Hospital.
- The study included all female index cases of genital tuberculosis over a twelve-year period.
Main Results:
- Forty cases of GTB were identified, predominantly in women aged 25-45 years.
- Infertility (42.5%) and abdominal pain (42%) were the most frequent symptoms; fever, ascites, and irregular bleeding were also noted.
- Standard treatment involved nine months of antituberculous drug therapy, resulting in only three successful pregnancies.
Conclusions:
- Genital tuberculosis should be considered in the differential diagnosis of female infertility.
- Effective management strategies are needed to improve pregnancy outcomes in women with GTB.