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Antiviral amentoflavone from Selaginella sinensis
1Department of Biology and Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, PR China.
Biological & Pharmaceutical Bulletin
|March 21, 2001
Abstract:
Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 microg/ml. The contents of amentoflavone in nine species of Selaginella were determined by reversed-phase HPLC. S. sinensis showed a higher content of 1.13%.