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In vitro activities of linezolid against multiple Nocardia species
B A Brown-Elliott1, S C Ward, C J Crist
1Department of Microbiology, University of Texas Health Center, Tyler, Texas 75708, USA. barbara.elliot@uthct.edu
Antimicrobial Agents and Chemotherapy
|March 21, 2001
Abstract:
Linezolid was tested by broth microdilution against 140 clinical Nocardia isolates belonging to seven species. The MIC at which 50% of the strains are inhibited (MIC50) and MIC90 for all species other than Nocardia farcinica were 2 and 4 microg/ml. Linezolid is the first antimicrobial agent demonstrated to be active against all Nocardia species.