Severe falciparum malarial complications in Ukhrul, Manipur
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Published on: May 16, 2013
S A Chishti1, L Duidang, A Kasar
1District Hospital, Ukhrul.
Abstract:
Development of complications is very common among the patients suffering from Plasmodium falciparum infection. A total of 64 patients of Plasmodium falciprum infections were admitted to the District Hospital, Ukhrul, during the period of 1st May 1996 to 15th June 1999; 9.37% patients do not develop complication while the rest 90.63% developed one or more complications. The most common complication is anaemia accounting for 76.56% followed by cerebral malaria (59.38%). Other lesser complications were leucopenia (15.63%), thrombocytopenia (26.56%), adult respiratory distress syndrome (6.25%). There is no single record of blackwater fever, 12.5% died due to development of multiple complications like severe haemolytic anaemia, haemolytic jaundice, cerebral malaria and acute renal failure. This study confirms presence of severe and complicated falciparum malaria in this part of the country.
Insights
Complicated Plasmodium falciparum malaria is prevalent, with over 90% of patients developing complications like anemia and cerebral malaria. Severe cases led to fatalities, confirming the severity of falciparum malaria in the region.
Area of Science:
- Tropical Medicine
- Infectious Diseases
- Malariology
Background:
- Plasmodium falciparum infections frequently lead to severe complications.
- Understanding complication patterns is crucial for patient management and public health strategies.
Purpose of the Study:
- To investigate the incidence and types of complications in Plasmodium falciparum malaria patients.
- To assess the mortality associated with complicated malaria in Ukhrul District Hospital.
Main Methods:
- Retrospective analysis of 64 Plasmodium falciparum malaria cases admitted between May 1996 and June 1999.
- Documentation of patient demographics, clinical presentation, complications, and outcomes.
Main Results:
- Over 90% of patients (90.63%) developed one or more complications.
- Anemia (76.56%) and cerebral malaria (59.38%) were the most frequent complications.
- Mortality was observed in 12.5% of patients, often due to multiple severe complications.
Conclusions:
- Plasmodium falciparum malaria frequently presents with severe complications in this region.
- Anemia and cerebral malaria are the predominant complications, necessitating targeted interventions.
- The high complication rate underscores the need for enhanced malaria control and treatment protocols.
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