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Faecal candida and diarrhoea.

D Forbes1, L Ee, P Camer-Pesci

  • 1Department of Paediatrics, University of Western Australia, Princess Margaret Hospital for Children, GPO Box D184, Perth, Western Australia, 6001. david@paed.uwa.edu.au

Archives of Disease in Childhood
|March 22, 2001
PubMed
Summary
This summary is machine-generated.

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This study found that Candida species in the stool do not cause diarrhea in well-nourished children. While yeasts are common in children

Area of Science:

  • Pediatric Gastroenterology
  • Microbiology
  • Infectious Diseases

Background:

  • Candida species are commonly found in the stools of children experiencing diarrhea.
  • However, their role as enteropathogens causing diarrhea has not been definitively established.
  • This research investigates the hypothesis that fecal Candida may be a cause of childhood diarrhea.

Purpose of the Study:

  • To determine the prevalence of fecal Candida in children with diarrhea.
  • To examine the relationship between the presence of fecal yeasts and the occurrence of childhood diarrhea.

Main Methods:

  • A comparative study was conducted involving 107 children hospitalized with diarrhea and 67 age-matched controls without diarrhea.
  • Quantitative stool cultures for yeasts were performed.

Related Experiment Videos

  • Clinical and laboratory data were analyzed.
  • Main Results:

    • Yeast species, primarily Candida, were detected in 39% of children with diarrhea and 36% of controls.
    • Higher Candida concentrations were associated with recent antibiotic use (p=0.03) and the presence of other enteric pathogens (p<0.005).
    • No significant association was found with patient age, nutritional status, or diarrhea duration.

    Conclusions:

    • Candida species are not identified as a cause of diarrhea in well-nourished children.
    • The findings suggest that other factors are responsible for diarrhea in this population, despite the presence of Candida.