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Trimethylaminuria: the fish malodor syndrome.
1Section of Molecular Toxicology, Division of Biomedical Sciences, Imperial College School of Medicine, Sir Alexander Fleming Building, South Kensington, London, England.
Summary
Fish malodor syndrome, or trimethylaminuria, causes a strong fishy body odor due to excess trimethylamine. Recent research advances understanding and treatment of this metabolic disorder.
Area of Science:
- Biochemistry
- Genetics
- Metabolic disorders
Background:
- Fish malodor syndrome (trimethylaminuria) is a metabolic disorder.
- Characterized by excessive trimethylamine (TMA) in bodily secretions.
- TMA causes a potent fish-like body odor, impacting social and professional life.
Framework:
- Understanding of fish malodor syndrome has advanced.
- Progress spans clinical, epidemiological, biochemical, and genetic levels.
- This article reviews recent progress in fish malodor syndrome.
Implementation:
- Summarizes recent advancements in understanding fish malodor syndrome.
- Highlights different types of fish malodor syndrome.
- Draws attention to current patient treatment needs.
Implications:
- Improved understanding of fish malodor syndrome.
- Potential for better patient management and treatment strategies.
- Addresses the significant personal and social impact of the condition.