Related Experiment Video
Updated: Aug 19, 2026

Streamlined 3D Cerebellar Differentiation Protocol with Optional 2D Modification
Published on: December 9, 2017
Transient cytoplasmic bridges among the cells of developing cerebellum: a possible mode of induction for cell
Abstract:
In the developing cerebellum of neonate rats, membrane fusions and cytoplasmic bridges were observed between the pre-existing Purkinje cells and the migratory and differentiating granule cells. These ultrastructural specializations of the apposing membranes were seen to be transient in nature, and represented a developmental phenomenon. On the basis of literature available on this type of direct cell-to-cell interaction it is suggested that such transient cytoplasmic bridges may provide induction for differentiation from the pre-existing Purkinje cells to the undifferentiated cells.
Related Concept Videos
Determination
Cell Motility through Blebbing
Blebbing Through the Matrix
In multicellular...
Cytoskeletal Coordination in Cell Migration
iPS Cell Differentiation
Forced Transdifferentiation
Artificial transdifferentiation occurs...
Cellular Differentiation
A zygote is a...

