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Modern application of high voltage stimulation for enhanced healing of venous crural ulceration
A Franek1, A Polak, M Kucharzewski
1Katedra i Zaklad Biofizyki Lekarskiej, Slaska Akademia Medyczna, ul. Medyków 18, bud. C2, 40-752, Pl, Katowice-Ligota, Poland.
Insights
High voltage stimulation (HVS) significantly enhanced venous crural ulcer healing. Patients receiving HVS showed faster wound size reduction, improved pus cleansing, and greater granulation compared to conventional treatments.
Area of Science:
- Medical Science
- Wound Healing Research
- Biomedical Engineering
Background:
- Crural ulceration, particularly venous crural ulceration, presents a significant clinical challenge.
- Optimizing wound healing processes is crucial for patient outcomes and reducing healthcare burdens.
Purpose of the Study:
- To evaluate the efficacy of high voltage stimulation (HVS) as a therapeutic modality for accelerating the healing of crural ulcerations.
- To compare the effects of HVS with traditional treatments like topical medicine and Unna's boot.
Main Methods:
- A randomized controlled trial involving three groups of patients with venous crural ulceration.
- Group A received high voltage stimulation (100 V, doubled-peak monophasic impulses, 0.1 ms duration, 100 Hz frequency).
- Groups B and C served as controls, receiving topical medicine and Unna's boot, respectively.
Main Results:
- All groups demonstrated a significant reduction in wound size.
- Group A (HVS) exhibited the highest rate of wound area reduction and pus cleansing.
- Significantly greater granulation tissue formation was observed in Group A after two weeks (P<0.003).
Conclusions:
- High voltage stimulation is an effective method for enhancing the healing process of crural ulcerations.
- HVS offers a promising therapeutic option for improving wound healing rates and tissue regeneration in venous ulcers.
Abstract:
The objective of this paper was to evaluate the effect of high voltage stimulation (HVS) on the process of healing of crural ulceration. Three comparative groups of patients, A, B and C, were drawn at random from patients with venous crural ulceration. Thirty-three patients in group A were subjected to treatment with HVS. In the course of treatment, doubled-peak monophasic impulses of a total duration of 0.1 ms and frequency of 100 Hz were applied. The voltage was 100 V. Group B, made up of 32 patients treated with topically applied medicine, and group C, made up of 14 patients treated with Unna's boot were used as control. In all patients in all groups (A, B and C) a significant reduction in wound size in relation to baseline was found. The rate of wound area change was highest in group A. The rate of pus cleansing was significantly highest in group A. The degree of granulation after 2 weeks was significantly greater in group A than in the other groups (P<0.003). High voltage stimulation was an efficient method of enhancement of the healing of crural ulceration.