Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Journal impact factors: a 'bioequivalence' issue?

A Rostami-Hodjegan1, G T Tucker

  • 1University of Sheffield, Section of Molecular Pharmacology and Pharmacogenetics, Clinical Sciences Division, The Royal Hallamshire Hospital, Sheffield S102JF, UK.

British Journal of Clinical Pharmacology
|March 22, 2001
PubMed
Summary

Journal Impact Factors (JIFs) do not accurately reflect individual research impact due to wide citation variability. Log-transforming citation data reveals smaller differences between clinical pharmacology journals, suggesting a more equitable comparison.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2020
Same author

Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method.

The AAPS journal·2019
Same author

Development and applications of a physiologically-based model of paediatric oral drug absorption.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2018
Same author

Application of the MechPeff model to predict passive effective intestinal permeability in the different regions of the rodent small intestine and colon.

Biopharmaceutics & drug disposition·2017
Same author

Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.

Clinical pharmacology and therapeutics·2017
Same author

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2016

Area of Science:

  • Bibliometrics
  • Scholarly Communication
  • Research Evaluation

Background:

  • Journal Impact Factors (JIFs) are widely used by institutions to assess the quality of individual research output.
  • Despite emphasis on cautious use, formal analyses of JIFs' validity for individual research assessment are limited.

Purpose of the Study:

  • To investigate the validity of using JIFs as a measure of individual research impact.
  • To analyze citation profiles of three clinical pharmacology journals.

Main Methods:

  • Compared citation patterns of 120 papers from Clin Pharmacol Ther, Br J Clin Pharmacol, and Eur J Clin Pharmacol across multiple years.
  • Utilized an analogy with drug pharmacokinetics (lag-time, Cmax, tmax, t(1/2), AUC(t)) to analyze citation-time profiles and assess 'bioequivalence'.

Related Experiment Videos

Main Results:

  • Citation distributions for individual publications were highly variable and skewed across all journals.
  • Wide 90% confidence intervals for JIFs of individual publications indicated significant variability (e.g., 0.24-16.94 for CPT).

Conclusions:

  • JIFs are not a reliable indicator of an individual paper's impact.
  • Log-transforming citation data, analogous to bioequivalence testing, reveals smaller absolute differences between clinical pharmacology journals.
  • This transformation better represents the likelihood of citation for a median article, suggesting a more equitable comparison of journal impact.