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Related Experiment Videos

Tuberculous gumma following venepuncture.

D Vidal1, M Barnadas, M Pérez

  • 1Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Sant Antoni M Claret 167, 08025 Barcelona, Spain.

The British Journal of Dermatology
|March 22, 2001
PubMed
Summary

Tuberculosis can manifest in the skin, even years after initial infection. A rare skin form, tuberculous gumma, can develop after minor trauma like a blood draw and resolves with standard treatment.

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Tuberculosis (TB) typically affects the lungs but can manifest in extrapulmonary sites.
  • Cutaneous TB is rare, often presenting as chronic, non-healing lesions.
  • Previous injury is a potential trigger for localized TB reactivation.

Observation:

  • An 88-year-old male presented with a 2-year history of a growing, ulcerated nodule on his left wrist.
  • The lesion appeared after a venous blood test, suggesting a potential inoculation site.
  • Skin biopsy revealed granulomas, but initial stains were negative.

Findings:

  • Cultures from the skin biopsy confirmed the presence of Mycobacterium tuberculosis.
  • Bone and joint involvement were ruled out through imaging.

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  • The patient achieved complete healing after 6 months of standard antituberculous therapy.

    • Implications:

    • This case highlights Mycobacterium tuberculosis as a cause of cutaneous gumma.
    • Minor trauma can lead to localized reactivation of tuberculosis in susceptible individuals.
    • Standard antituberculous treatment is effective for managing cutaneous tuberculous gumma.