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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Granular cell tumor of the thyroid
1Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada V5Z 1M9.
Archives of Pathology & Laboratory Medicine
|March 22, 2001
Summary
A rare granular cell tumor of the thyroid was found in a young woman. This case suggests a possible neural crest origin for certain thyroid tumors.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Granular cell tumors (GCTs) are rare neoplasms of uncertain origin.
- Thyroid gland neoplasms encompass a diverse range of pathologies.
Observation:
- A case of granular cell tumor of the thyroid gland in a 23-year-old woman is presented.
- The patient exhibited a painless neck mass with unremarkable health status.
- Fine-needle aspiration biopsy revealed thyroid epithelial cells with potential oncocytic changes.
Findings:
- This report details a second documented instance of granular cell tumor in the thyroid gland in English literature.
- The histological findings were consistent with granular cell tumor.
Implications:
- The occurrence of GCT in the thyroid supports theories of a neural crest origin for specific thyroid neoplasms.
- This case contributes to the understanding of rare thyroid pathologies and their potential origins.
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