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[A case of loiasis].

S Yara¹, F Higa, N Arakaki

¹First Department of Internal Medicine, University of the Ryukyus.

Kansenshogaku Zasshi. the Journal of the Japanese Association for Infectious Diseases

|March 23, 2001

Summary

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Loiasis, a parasitic infection common in Africa, was treated in Japan for the first time. Ivermectin (IVM) effectively reduced microfilaria counts in a patient with no adverse effects, suggesting its utility for loiasis treatment.

Area of Science:

Tropical medicine
Parasitology
Infectious diseases

Background:

Loiasis, caused by the parasitic worm *Loa loa*, is endemic in Central and West Africa.
Imported cases are rare in non-endemic regions like Japan, with only three previously reported.
This report details a unique case of loiasis diagnosed and treated in Japan.

Observation:

A 28-year-old male from Gabon presented with characteristic eye symptoms of loiasis.
The patient was diagnosed with *Loa loa* infection.
This marked a rare instance of loiasis in Japan.

Findings:

The patient received Ivermectin (IVM) therapy, a treatment gaining global attention for filarial diseases.
IVM treatment led to a significant decrease in blood microfilaria counts.

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No adverse effects were observed during or after the treatment course.

Implications:

This case highlights Ivermectin as a potentially effective treatment for loiasis.
The successful use of IVM in Japan broadens its therapeutic application for imported parasitic infections.
Further research is warranted to confirm IVM's efficacy and safety profile for loiasis globally.