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Biotransformation of podophyllotoxin to picropodophyllin by microbes
1School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083, P.R. China.
Journal of Asian Natural Products Research
|March 23, 2001
Abstract:
Biotransformation of podophyllotoxin (PT) by several microbial species has been investigated. Among the fungi tested, it was found that Penicillium strains can isomerize PT to picropodophyllin (PPT) in 8% yield and other strains also transform the substrate into the same product but with lower yield.