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Updated: Aug 8, 2026
12:23
Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
["Idiopathic" acute optic neuropathies in children]
1Clinique Ophtalmologique à l'Université de Paris V-Cochin Port-Royal-Centre National d'Ophtalmologie des Quinze-Vingts, 28 rue de Charenton-75571 Paris.
Bulletin De L'Academie Nationale De Medecine
|March 23, 2001
Summary
Acute optic neuritis in children often presents bilaterally and can follow viral infections or hepatitis B vaccination. While most children recover vision, some develop multiple sclerosis, a rate lower than in adults.
Area of Science:
- Ophthalmology
- Neurology
- Pediatrics
Context:
- Retrospective study of 27 children (mean age 10) with acute optic neuritis from 1982-1997.
- Investigated symptoms, associations, and outcomes of pediatric optic neuritis.
- Compared pediatric to adult multiple sclerosis incidence.
Purpose:
- To characterize acute optic neuritis in children.
- To evaluate the association with viral infections and hepatitis B vaccination.
- To assess visual recovery and multiple sclerosis development post-optic neuritis.
Summary:
- Acute optic neuritis in children often presents bilaterally, frequently associated with viral infections or hepatitis B vaccination.
- Magnetic resonance imaging revealed hyperintense nodular abnormalities in 9 of 20 children.
- Most children (23/27) achieved excellent visual recovery; 4 developed multiple sclerosis.
- Corticosteroids, including intravenous methylprednisolone, were used in 23 cases.
Impact:
- Highlights the distinct presentation and outcomes of optic neuritis in pediatric populations.
- Informs clinical management and prognosis for children experiencing vision loss due to optic neuritis.
- Contributes to understanding the relationship between optic neuritis and subsequent multiple sclerosis development in children.
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