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A case of pulmonary toxicity associated with G-CSF and doxorubicin administration
C F Eisenbeis1, D Winn, S Poelman
1Department of Medicine, University of Chicago Medical Center, Chicago, Ill., USA.
Annals of Hematology
|March 23, 2001
Abstract:
The cytokine growth factor, G-CSF (granulocyte colony-stimulating factor), is commonly used in oncologic practice and is generally believed to be a safe agent to administer. We describe here a case of pulmonary toxicity associated with the concurrent administration of G-CSF and doxorubicin. We contend that G-CSF contributed to the life-threatening lung injury in our patient, and discuss additional reports in the literature of pulmonary toxicity associated with the use of this agent.