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Updated: Jul 27, 2026

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion
Published on: July 17, 2012
Myocardial contusion presented as acute myocardial infarction after chest trauma
A Tsoukas1, A Andreades, C Zacharogiannis
1Cardiology Department and Intensive Care Unit, Asclepion Voulas Hospital, Athens, Greece. thanos@fnet.gr
Insights
Blunt chest trauma can cause acute myocardial infarction and heart failure, even with normal coronary arteries. This case highlights the potential for delayed, fatal cardiac events following initial recovery from chest trauma.
Area of Science:
- Cardiology
- Trauma Medicine
- Cardiac Rehabilitation
Background:
- Blunt chest trauma can lead to cardiac complications.
- Myocardial infarction and heart failure are serious cardiac events.
Observation:
- A 46-year-old male experienced acute myocardial infarction and congestive heart failure post-blunt chest trauma.
- Initial evaluation showed anterior myocardial infarction, impaired left ventricular function, and normal coronary arteries.
- The patient initially responded to a low-intensity rehabilitation program.
Findings:
- Despite initial recovery, the patient later presented with acute pulmonary edema and cardiogenic shock.
- Cardiopulmonary resuscitation was unsuccessful, leading to mortality.
- This suggests a potential for delayed, severe cardiac sequelae after trauma.
Implications:
- This case underscores the importance of long-term cardiac monitoring after blunt chest trauma.
- It highlights that seemingly resolved cardiac issues post-trauma can have fatal recurrences.
- Further research into the mechanisms and long-term management of post-traumatic cardiac dysfunction is warranted.
Abstract:
A 46-year-old male patient developed an acute myocardial infarction and congestive heart failure following blunt chest trauma. Electrocardiogram (ECG) revealed acute anterior myocardial infarction. Echocardiography showed akinesis of interventricular septum, dyskinesis in apical anterior wall, and severe impairment of left ventricular overall systolic function. Coronary angiography revealed normal coronary arteries. The patient followed a low-intensity physical medicine rehabilitation program. Follow-up was without new complications or deterioration of congestive heart failure. Five months later the patient presented with fulminant acute pulmonary edema and cardiogenic shock. Cardiopulmonary resuscitation was unsuccessful.
Related Concept Videos
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome IV: Interprofessional Care
Introduction Cardiac Emergencies

